Overview In this role you support the Formulation team to develop and optimize lipid nanoparticles (LNPs) for nucleic acid delivery. You work closely with senior scientists to execute experiments, apply DoE-driven screening, and help move early-stage formulations toward scalable solutions. You will analyze data, maintain rigorous records, and collaborate across functions to advance a non-viral delivery platform. This position offers hands-on growth in a fast-paced, impactful field.
Responsibilities- Execute and optimize LNP/tLNP formulation and characterization for in vitro and in vivo studies under guidance
- Lead Design of Experiment (DoE) screening campaigns to identify optimal compositions and processing parameters
- Collaborate with cross-functional teams to fulfill formulation requests
- Support early-stage formulation development, including cryoprotection, scale-up, and stability studies
- Maintain detailed records of formulation activities and results
- Analyze, interpret, and present experimental data to the formulation team
- Contribute to routine lab management including inventory, buffer prep, and autoclaving
Key requirements- Bachelor in Chemistry, Biochemistry, Chemical Engineering, or related discipline with 4+ years in biopharma, or Master with 1+ years in industry
- At least 2 years hands-on LNP formulation and nucleic acid encapsulation experience (mRNA, siRNA, or DNA)
- Proficiency with LNP characterization methods (DLS, zeta potential, Ribogreen)
- Strong Excel skills; experience with statistical/data analysis software (e.g., JMP, Prism)
- Attention to detail, reproducibility of data, organizational skills, and clear communication in a fast-paced team environment
- Preferred: experience with targeted LNPs and immune-cell delivery (e.g., Ab, Fab, ScFv, VHH)
- strong collaboration and teamwork
- excellent data interpretation and communication
- detail-oriented and well-organized
- LNP formulation and encapsulation
- DoE-based screening
- Dynamic Light Scattering (DLS)
