Overview In this role you will lead safety science and pharmacovigilance efforts across Revolution Medicines' portfolio, supporting both early and late-stage development. You will provide safety oversight for clinical studies, contribute to trial documents, and collaborate with cross-functional teams to manage risk and ensure compliant drug safety practices. You will perform signal detection and risk mitigation, while communicating safety insights to stakeholders. This is an opportunity to shape safety strategy in a fast-paced, mission-driven oncology company.
Compensation / Benefits- base pay eligible for up to $186,000-$233,000 USD
- competitive cash compensation
- significant equity awards
- strong benefits
- learning and development opportunities
- hybrid work arrangement ()
Responsibilities- Oversee safety for clinical studies and contribute to protocols, IBs, ICFs, DSURs
- Perform safety surveillance and review ICSRs; support risk management and communication
- Prepare safety data summaries and present to stakeholders
- Identify safety signals and contribute to escalation to safety governance committees
- Update core safety information and key safety documents (DSURs, ICH-RMPs, labeling)
- Ensure safety components of study reports and regulatory submissions are accurate
- Collaborate with cross-functional teams and external partners; ensure compliance with GVP, GCP
- Contribute to SOP development and safety science processes
Key requirements- Postgraduate qualification in life sciences or health profession (e.g., MD, PharmD, PhD/MSc)
- 5+ years in drug development with at least 3 years in drug safety
- Strong understanding of PV, GVP, GCP, and safety operations
- Proven ability to lead and influence in a fast-paced environment
- Excellent written and verbal communication and presentation skills
- Ability to work independently and in cross-functional teams
- Strong organizational skills and ability to interpret trial data and identify trends
- collaborative
- strong communication
- stakeholder management
- pharmacovigilance
- risk management
- signal detection and evaluation
