Overview As a Scientist specializing in LC-MS/MS, you will drive quantitative bioanalysis and metabolite profiling within Frontage's DMPK-focused teams. You will lead LC-MS/MS projects, optimize sample prep and analytical methods, and collaborate with cross-functional teams to translate data into actionable insights for drug safety and efficacy. This role blends hands-on instrument work with data interpretation, reporting, and client interactions. You'll stay at the forefront of LC-MS/MS tech to support high-quality, compliant deliverables.
Compensation / Benefits- health and dental insurance
- 401(k) plan
- health insurance
- short- and long-term disability insurance
- life insurance
Responsibilities- Develop and optimize sample preparation and analytical methods for quantitative drug measurement and metabolite profiling using LC-MS/MS and HRMS
- Lead and execute LC-MS/MS-based projects in a timely and high-quality manner
- Interact with clients to provide actionable insights on method development and sample analysis challenges
- Operate, maintain and troubleshoot LC-MS/MS instruments; serve as instrument lead as needed
- Prepare and review scientific reports, presentations, and regulatory documents to ensure accuracy and compliance with industry standards
- Stay updated on advancements in LC-MS/MS technologies and methodologies
- Collaborate with cross-functional teams and provide technical guidance when needed
- Mentor and train junior lab staff
Key requirements- Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
- Solid hands-on experience with LC-MS/MS-based bioanalytical method development including sample preparation, instrument operation and data processing
- Proven track record operating LC-MS/MS systems in a bioanalytical lab
- Strong expertise in drug metabolism and biotransformation, with hands-on experience in metabolite identification using LC-MS/MS and HRMS
- Demonstrated ability to analyze and interpret complex mass spectrometry data and provide detailed reports
- Excellent communication skills and ability to work both independently and collaboratively in a cross-functional team environment
- Experience in pharma or biotech environment is a plus
- excellent communication
- teamwork/collaboration
- mentoring and training junior staff
- LC-MS/MS
- HRMS
- bioanalytical method development
