Overview As a Research Scientist II in the Synthesis Technologies Team of Global Discovery Chemistry at NIBR (Cambridge), you drive the synthesis and purification of pharmaceutically relevant molecules from mg to multi-gram scale. You will apply innovative methods, troubleshoot routes, and collaborate across global teams to advance small-molecule drug discovery. You contribute to safe, efficient methods and structural elucidation within a fast-paced research environment. This role offers the opportunity to influence project outcomes and grow within a mission to discover transformative medicines.
Compensation / Benefits- salary range $81,200 - $150,800
- performance-based cash incentive
- eligibility for annual equity awards
- comprehensive benefits package (health, life, disability)
- 401(k) with company contribution and match
- generous time off package
Responsibilities- Conduct task-oriented synthesis and purification from milligram to multi-gram scale
- Anticipate synthetic pitfalls and optimize routes/conditions
- Explore and deploy cutting-edge synthetic methods for building blocks and drug substances
- Collaborate with internal and external chemistry teams
- Perform structural and stereochemical elucidation
- Adhere to laboratory safety policies
Key requirements- BS or MS in synthetic organic chemistry with 2-5 years of postgraduate experience
- Strong working knowledge of synthetic organic methodology and multi-step preparation of drug substances
- Excellent observational, organizational, data management, and documentation skills
- Desire for green and sustainable synthesis methods (preferred)
- Outstanding communication skills for cross-functional collaboration with medicinal chemistry teams
- collaboration
- communication
- problem-solving
- synthetic organic chemistry
- multi-step synthesis
- purification
