P
Not Specified Permanent

Washington, Washington DC · USA job

Senior Scientist, Conjugation Process Development

Pfizer

Washington, Washington DC

Job description

Overview

In this role you will lead ADC process development within Pfizer's Conjugation Process Development team, shaping early to late-stage programs. You'll apply expert scientific judgment to optimize conjugation processes, mentor colleagues, and forecast resources to meet project milestones. You'll work across multidisciplinary teams to deliver high-quality ADC products that address cancer and improve patient outcomes. This is a hands-on, impact-driven position at the heart of Pfizer's R&D mission.

Compensation / Benefits
  • competitive base salary
  • annual bonus target 12.5%
  • 401(k) with Pfizer match and retirement contributions
  • paid vacation, holidays and personal days
  • paid caregiver/parental and medical leave
  • comprehensive health benefits (medical, dental, vision)
Responsibilities
  • Independently design, execute and interpret studies to answer defined questions within timeframes
  • Monitor results, troubleshoot, and develop corrective actions
  • Facilitate technology/assay transfers internally and externally
  • Contribute to department and project teams and represent the group on cross-functional teams
  • Present at national/international forums when appropriate
  • Author and review technical reports, manufacturing documents, regulatory submissions and publications
  • Identify and propose process improvement and technology development opportunities
Key requirements
  • Bachelor's/Master's/PhD with relevant years of experience as specified
  • Degree in chemistry, biochemistry, chemical engineering, or related field
  • Direct experience with antibodies, proteins, and/or bioconjugation
  • Strong knowledge of analytical protein characterization (HPLC, IEF, CE-SDS)
  • Willingness to work with highly potent cytotoxic molecules
  • Ability to perform complex data analysis
  • Foundational understanding of organic chemistry, reaction mechanisms, and process development
  • Excellent oral and written communication
  • Mentoring and people development
  • Cross-functional collaboration
  • Antibodies, proteins, and bioconjugation expertise
  • Bioconjugation chemistry and protein modification
  • Analytical technologies for protein characterization (HPLC, IEF, CE-SDS)

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