Overview In this role you will contribute to discovering and optimizing drug candidates by leading cell-based and molecular assays for pre-clinical development. You'll work within a multidisciplinary team to advance targeted protein degradation strategies and generate robust data to support decision-making. The position offers meaningful work in a purpose-driven culture focused on patients, growth, and collaboration. You will leverage high-quality science to drive impactful therapeutic discovery at scale.
Compensation / Benefits- comprehensive benefit plans
- wellbeing and retirement protections
- Flexible Time Off (FTO) for U.S.-based exempt staff
- 11 paid company holidays annually
- paid time off for volunteering and flexible schedules
- Global Shutdown between Christmas Day and New Year's Day
Responsibilities- Design, develop, and implement high-throughput cell-based assays to evaluate drug candidates
- Conduct mechanism of action studies to understand biological activity and target engagement
- Generate and characterize stable cell lines using lentiviral and PiggyBac gene transfer
- Maintain cell culture quality and reproducibility for drug discovery work
- Perform molecular biology and protein analysis including DNA/RNA/protein extraction, immunoblotting, immunoprecipitation
- Assist senior researchers in executing experiments and reporting results
- Review literature and internal practices to improve productivity and quality
- Write protocols and technical reports; communicate results through reports and presentations
Key requirements- BS with 5+ years post-graduation or MS with 3+ years post-graduation
- expertise in mammalian cell culture, multi-well assays, immunoblotting, stable cell line generation, transfection, and basic molecular biology
- experience with medium/high-throughput screening (preferred)
- familiarity with targeted protein degradation assays (plus)
- knowledge of automation instruments and multi-mode plate readers
- strong problem-solving, organization, and communication skills
- team player with ability to work independently and manage multiple tasks
- strong communication skills (verbal and written)
- collaborative mindset
- self-driven and proactive
- mammalian cell culture
- multi-well plate-based cellular assays
- immunoblotting
