Overview In this role you will advance dark proteome research in cancer as part of the Cancer Grand Challenges ILLUMINE team, collaborating with the GENCODE consortium. You will work on cancer-related projects focusing on non-canonical open reading frames, RNA translational control, and RNA diagnostics. You'll perform wet-lab and tissue culture work, with a multi-omic approach including ribosome profiling, RNA-sequencing, and epitranscriptomic profiling, contributing to data-driven discoveries. You will operate lab systems, document results, and support cross-functional planning, all while fostering a collaborative and scientifically adventurous lab culture.
Responsibilities- Conduct wet-lab molecular biology and tissue culture experiments
- Advance cancer-related projects on non-canonical open reading frames, RNA translational control, and RNA diagnostics
- Apply multi-omic methods (ribosome profiling, RNA-seq, epitranscriptomic profiling)
- Perform tissue culture, in vitro bioassays, and small-molecule treatments
- Maintain and operate laboratory equipment; document, analyze, and report data
- Participate in team meetings and contribute to experimental planning
- Nurture a collaborative, supportive lab culture and develop collaborations
- Handle additional related tasks as needed
Key requirements- Bachelor's degree in life sciences
- 4-5 years of experience in a related field
- Equivalent combination of education and experience may be accepted
- exceptional organizational skills
- critical thinking
- excellent communication across staff and external contacts
- mammalian tissue culture
- DNA/RNA molecular assays (PCR, RNA extraction, DNA extraction)
- -omics technologies
