Overview As a Scientist in Oncology Research at Amgen, you will contribute to discovering and validating novel oncology targets and advancing small-molecule therapeutics. You join a cross-functional discovery team to perform in vitro studies, assess mechanisms of action, and generate data that guides target validation and drug discovery. You will leverage literature and databases to explore emerging hypotheses and shape target ideation. Your work supports a mission-driven culture that values collaboration, scientific rigor, and translational impact in cancer therapy.
Compensation / Benefits- comprehensive employee benefits package
- Retirement and Savings Plan with company contributions
- group medical, dental and vision coverage
- life and disability insurance
- flexible spending accounts
- stock-based long-term incentives
Responsibilities- Develop and conduct in vitro studies to investigate target biology and mechanisms of action
- Evaluate early-stage therapeutic molecules and generate actionable data for target validation
- Identify and assess emerging target hypotheses using literature and databases
- Maintain thorough research records and communicate findings internally and externally
- Contribute data and writing to peer-reviewed publications
Key requirements- Doctorate degree or Master's degree with 2 years of relevant laboratory experience or Bachelor's degree with 4 years of relevant laboratory experience
- Strong background in cancer biology, signaling pathways, and cell cycle
- Experience with standard cell and molecular biology techniques (cell culture, western blotting, immunofluorescence, qPCR, flow cytometry)
- Experience with high-throughput assays (CTG, AlphaLISA, MSD) is a plus
- Mammalian cell culture experience and familiarity with gene function assays (RNAi, CRISPR) including lentivirus
- Familiarity with genomic data analysis tools (DepMap, cBioPortal, OmicsSoft) and AI-enabled research tools (CODEX)
- Track record of independent scientific achievement with publications or contributions to drug discovery
- Ability to communicate results and collaborate across a cross-functional team
- Collaborative mindset
- Critical thinking
- Scientific curiosity
- Cancer biology
- Target identification and validation
- Cell culture and molecular biology techniques
