Overview In this role you will support early cardiovascular gene therapy programs by performing optimization, development, and data delivery. You will work within a cross-functional R&D team to enable preclinical studies and platform support, driving reproducible data. You will apply a range of molecular and cell biology techniques to extract and analyze biomolecules and contribute to protocol improvements. This position offers hands-on impact in a leading gene therapy program and room to grow in a collaborative, fast-paced team.
Responsibilities- Design, plan, and execute experiments to analyze protein, RNA, and DNA from in vitro and in vivo studies for gene therapy programs
- Independently perform techniques such as cell culture, nucleic acid/protein extraction, qPCR/ddPCR, ELISA, SDS-PAGE, and Western blot/Jess
- Process and analyze large numbers of samples with high quality and consistency
- Maintain accurate electronic lab notebooks and support databases, inventories, and reagent tracking
- Assist in developing and optimizing experimental protocols and contribute to assay/workflow improvements
- Generate high quality, reproducible data and assist in data analysis, interpretation, and reporting
- Contribute to study reports and protocols; ensure a safe, organized lab environment and equipment maintenance
- Coach and support peers to enable efficient day-to-day workflows
- Follow established protocols with minimal supervision and deliver reliable results
Key requirements- MS in Molecular Biology, Biochemistry or related field; or BS with 2+ years' relevant lab experience; or High School Diploma with 6+ years' relevant lab experience
- Hands-on molecular biology experience (DNA/RNA isolation, SDS-PAGE, qPCR/ddPCR, Western blot)
- Experience with mammalian cell culture and aseptic technique
- Ability to follow established protocols and deliver reproducible results
- Strong data collection, documentation, and reporting skills
- Ability to work independently and as part of a team
- Adaptability and willingness to learn across diverse workflows
- DNA/RNA isolation
- SDS-PAGE
- qPCR/ddPCR (including ddPCR)
