A
Not Specified Permanent

San Jose, California · USA job

Sr. Principal Scientist, Amazon Health Science & Analytics

Amazon

San Jose, California

Job description

Overview

As a senior AI/ML researcher, you will define the long-horizon ML vision for a healthcare-focused organization, guiding the development of a domain-specific foundation model and a high-reliability inference system. You will shape how frontier models are leveraged, decide when to build proprietary domain models, and sequence capabilities into monetizable, customer-facing features while adhering to safety and regulatory constraints. You'll serve as a senior technical advisor on frontier-model integration, data strategy, evaluation, and safety architecture, partnering with product, engineering, clinical, and compliance teams to ensure safe, reliable, and differentiating AI capability over time.

Responsibilities
  • Architect and guide a long-horizon ML strategy for healthcare foundation models
  • Define technical vision for frontier-model use and proprietary domain models
  • Oversee data strategy, evaluation harness design, and safety architecture
  • Lead cross-functional collaboration with product, engineering, clinical, and compliance teams
  • Ensure AI systems are safe, reliable, economically viable, and capable of long-term differentiation
  • Advise engineering and science teams on ML systems engineering, training, and deployment
  • Drive high-stakes, regulated-domain ML shipping and governance practices
  • Balance research depth with pragmatic product sense to build enduring capability
Key requirements
  • 10+ years in AI domains
  • 5+ years of language/multimodal model tuning and optimization
  • Proven track record shipping large-scale AI/ML products
  • Experience training or adapting large-scale models (LLMs, multimodal, MoE)
  • Strong grounding in distributed training, RLHF/DPO, retrieval and knowledge integration
  • Experience with evaluation harness design and ML systems engineering
  • Familiarity with clinical data, workflow constraints, and safety/regulatory practices (ISO-aligned or equivalent)
  • cross-functional collaboration
  • storytelling and technical leadership
  • pragmatic product sense
  • large-scale model training/adaptation
  • RLHF/DPO
  • retrieval and knowledge integration

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