Overview As Senior Principal Scientist, you will lead upstream bioprocessing efforts for biologics, shaping strategy and translating it into scalable, robust manufacturing processes. You will collaborate with cross-functional teams to advance early- and late-stage programs, while exploring next-generation biomanufacturing technologies. Your leadership will drive scientific innovation, process optimization, and regulatory readiness across the Biologics platform. This role offers impact in accelerating patient access to biotherapeutics and advancing cutting-edge bioprocessing capabilities. You will work in a collaborative, inclusive environment that values mentorship and cross-disciplinary partnership.
Compensation / Benefits- salary and bonus
- long-term incentive
- comprehensive benefits package
- medical, dental, vision
- retirement benefits (401(k
- paid holidays, vacation, compassionate and sick days
Responsibilities- Shape and drive innovation across the Biologics pipeline and strategy
- Lead development of robust, scalable upstream processes for biologics across clinical stages
- Advance process characterization and support regulatory filings for commercialization
- Improve upstream processes for efficiency and cost-effectiveness through research and new technologies
- Collaborate with academia, industry, and vendors to adopt novel process technologies
- Contribute to strategic initiatives and guide project execution with senior leadership
- Plan and execute projects with strong organizational and problem-solving skills
- Stay current on scientific and regulatory landscape and build reputation through conference activity
- Represent BPR&D as an upstream bioprocess expert in cross-functional teams
- Supervise and develop a team of 3-5 scientists, fostering growth and collaboration
- Mentor colleagues to maximize talent development and promote inclusion and safety
Key requirements- Strong cell-culture process development expertise for biologics, including fed-batch and bioreactor scale-up
- Experience leading design, execution, analysis, and documentation of cell-culture process development
- Track record of upstream bioprocessing achievements and peer-reviewed dissemination
- Knowledge of biologics CMC development
- Ability to manage multiple objectives under tight timelines in a dynamic setting
- Experience leading cross-functional, matrixed teams
- Demonstrated scientific leadership with measurable program impact
- Creative, initiative-driven problem solver
- Supervise and mentor scientists to support talent development
- Excellent interpersonal and communication skills
- leadership
- collaboration
- communication
- cell-culture process development
- upstream bioprocessing
- bioreactors
