S
Not Specified Permanent

Cambridge, Massachusetts · USA job

Senior Principal Scientist, Type 2 Immunology

Sanofi

Cambridge, Massachusetts

Job description

Overview

In this role, you drive translational strategies bridging preclinical research with clinical development to inform decision-making and asset lifecycle management. You will lead preclinical programs, work across Development, Medical Affairs, and Commercial teams, and mentor junior scientists within a highly collaborative environment. You'll leverage AI-powered platforms and single-cell/multi-omics approaches to generate actionable insights that shape the portfolio's direction. This position offers a meaningful, science-driven path at Sanofi's Cambridge campus with broad cross-functional impact.

Compensation / Benefits
  • high-quality healthcare
  • wellbeing programs
  • 14 weeks gender-neutral parental leave
  • rewarding growth opportunities
  • competitive compensation
  • career mobility support
Responsibilities
  • Lead preclinical programs from hypothesis generation through execution and integrate findings into clinical strategy
  • Support early clinical and/or late-stage or marketed programs, translating clinical insights back to research
  • Design and execute research programs with Development, Medical Affairs, and Commercial teams as part of IEGP
  • Formulate hypotheses independently and conduct experiments using murine and human immunology approaches
  • Develop novel in vitro and in vivo assays and apply advanced technologies (single cell, multiomics, imaging)
  • Lead cross-functional collaborations and manage stakeholder relationships across a global matrix
  • Communicate findings clearly to technical and non-technical audiences
  • Mentor and develop junior team members
  • Stay abreast of scientific advances and contribute to group strategy
  • Maintain laboratory activity while providing scientific leadership; bench engagement as needed
  • Ensure safety, proper laboratory conduct, ELN documentation, and compliance with conduct policies
Key requirements
  • PhD with 8+ years of relevant experience in academia or biopharma (or equivalent: Master + 10 years; Bachelor + 12 years)
  • Experience leading preclinical research projects or as a key contributor to clinical programs
  • Proven translational research track record supporting clinical development and/or lifecycle management
  • Strong expertise in human and murine immunology and inflammatory disease pathways
  • Experience with single-cell approaches (flow cytometry, scRNA-seq), molecular techniques, and multi-omics
  • Proven ability to work in cross-functional, matrixed environments with Development, Medical Affairs, and/or Commercial teams
  • Excellent stakeholder management and communication across diverse audiences
  • Collaborative team player with mentorship capabilities and commitment to developing junior scientists
  • Track record of scientific publications in high-impact journals
  • Experience with external academic collaborations and CROs
  • collaborative mindset
  • strong communication
  • mentorship
  • flow cytometry
  • scRNA-seq
  • single-cell approaches

Explore related USA jobs

Similar jobs you may like

Related roles with a similar title and location.

Same category Same location Same country

Phlebotomy Lab Manager - Boston, MA

KA Recruiting Inc.

Boston, Massachusetts, United States · 02115

Same category Same location Same country

Laboratory Supervisor OR Lab Supervisor on Day Shift

KA Recruiting Inc.

Mansfield, Massachusetts, United States · 02048

Same category Same location Same country

Laboratory Supervisor OR Chemistry Lab Supervisor in New England

KA Recruiting Inc.

Attleboro, Massachusetts, United States · 02703

Same category Same location Same country

Microbiology or Molecular Lab Supervisor on Day Shift

KA Recruiting Inc.

Fall River, Massachusetts, United States · 02721

Same category Same location Same country

Microbiology OR Molecular Lab Supervisor On Day Shift

KA Recruiting Inc.

Foxboro, Massachusetts, United States · 02035

Same category Same location Same country

Clinical Laboratory Technologist in Eastern Massachusetts

KA Recruiting Inc.

Taunton, Massachusetts, United States · 02780

Same category Same location Same country

Lab Manager Phlebotomy - Boston, MA

KA Recruiting Inc.

Boston, Massachusetts, United States · 02115

Same category Same location Same country

Lead Research Scientist - Analytical Chemistry

FM

Norwood, Massachusetts, United States · 02062

Need help finding a job?

Chat with our AI assistant.