Director, Program Management

In this role you will drive cross-functional planning and execution for two assets across development stages. You will own the integrated development plan for the first ADC program as it transitions from early to late-stage, and also manage an early-stage radiopharmaceutical asset from candidate selection through IND-enabling activities. You will help shape the program management operating model and enable data-driven governance to support a growing pipeline. You will partner with R&D, CMC, Regulatory, Clinical, Quality, and external partners to translate strategy into actionable plans and decision-ready updates.

• Own the integrated development plan for the first ADC asset across clinical, nonclinical, CMC, and regulatory workstreams.
• Evolve the transition from early to late-stage development with governance cadence and staffing changes to meet late-stage needs.
• Maintain the integrated program timeline and critical path, identifying sequencing conflicts and long-lead items.
• Prepare for stage-gates and regulatory interactions with decision-ready materials.
• Manage the early-stage radiopharmaceutical program from candidate selection to IND-enabling activities and early clinical evaluation.
• Develop the early development plan covering discovery, nonclinical, CMC, regulatory strategy, and first-in-human readiness.
• Coordinate cross-functional workstreams into a single critical path and drive IND stage-gate readiness.
• Plan for radiopharmaceutical-specific operational and supply considerations.
• Represent CMC on the core product development team and own CMC deliverables, timelines, and risks.
• Liaise with contract manufacturing organizations and external partners; manage scope, deliverables, and schedule adherence.
• Direct the CMC budgeting process and manage spend to target.
• Coordinate and facilitate cross-functional meetings, capture decisions, and hold teams to commitments.
• Communicate program status to stakeholders and prepare dashboards and executive updates.
• Identify and mitigate program risks across technical, operational, supply, and regulatory dimensions.
• Develop budgets with Finance, manage resource planning, and protect critical path.
• Ensure complete and compliant documentation, adhering to regulatory requirements and GxP standards.
• Develop and improve the program management operating model, templates, and tools across the portfolio.
• Support additional PMO projects as the company grows.

• 8 to 10 years of project and program management experience in biotechnology or pharmaceutical industry
• Experience across multiple development stages and transitioning from early to late-stage
• Direct hands-on CMC project management, including manufacturing timelines and external partnerships
• Proven track record in leading cross-functional core teams in a matrixed environment
• Strong knowledge of drug development functions, regulatory expectations, and industry standards (FDA/EMA)
• Excellent cross-functional communication and relationship-building skills
• Ability to manage multiple priorities in a fast-paced setting; strong problem-solving and decision-making abilities
• Proficiency with project management tools (Smartsheet, MS Project, Asana) and MS Office Suite
• Preferred: antibody-drug conjugates, radiopharmaceuticals, oncology development, regulatory submissions (IND/CTA) and experience in a biotech environment
• Bachelor's degree in a technical or scientific field; advanced degree or PMP desirable

• cross-functional collaboration
• influencing at all levels
• problem solving
• Smartsheet
• MS Project
• Asana