Overview In this open-rank role, you will advance genome engineering efforts within Mayo Clinic Florida's expanding cell therapy program. You will collaborate with CAR-T and immune cell teams to translate gene-editing strategies into clinically meaningful cell therapies. Your work will span oncology and non-oncology indications, aiming to broaden therapeutic reach and improve persistence, safety, and efficacy. You will lead innovative pipelines from discovery toward early-phase trials, shaping the program's strategic growth and translational impact. Join a collaborative, mission-driven environment that values transformative science and inclusive mentorship.
Compensation / Benefits- Competitive startup and institutional support
- Investment in team science and program-building
- Access to a $1B+ annual research enterprise
- Infrastructure for IND-enabling studies and early-phase trials
- Exceptional benefits including retirement and pension programs
- Culture of innovation, inclusion, and cross-disciplinary collaboration
Responsibilities- Provide scientific leadership in genome engineering across the cell therapy ecosystem
- Collaborate with CAR-T and translational immunotherapy teams to develop next-generation engineered immune cell platforms
- Develop and optimize gene editing solutions (efficacy, durability, safety switches, multiplex editing, precision targeting)
- Build scalable, clinically translatable genetic engineering pipelines from discovery to early-phase trials
- Contribute to strategic growth and national visibility of Mayo Clinic Florida's Cell Therapy Program
- Mentor trainees, junior faculty, and research staff within a collaborative environment
- Engage in institutional initiatives aligned with Cure, Connect, and Transform healthcare through transformative science
- Integrate advanced genome engineering technologies with existing and emerging cell therapy platforms, including in vivo editing and stem cell modification
Key requirements- Doctoral degree in genetics, molecular biology, immunology, biomedical engineering, or related discipline
- Strong record of high-impact peer-reviewed publications in genome editing or immune engineering
- Sustained extramural funding appropriate to academic rank (e.g., NIH K award or equivalent for Assistant Professor; R01-level for higher ranks)
- Experience cross-disciplinary collaboration, particularly with immunotherapy or CAR-T research
- Evidence of scientific leadership and ability to build multidisciplinary programs
- Commitment to mentorship, education, and inclusive academic culture
- collaboration
- leadership
- mentorship
- genome engineering
- CRISPR/Cas systems
- base editing
