A
Not Specified Permanent

Thousand Oaks, California · USA job

Senior Scientist - Translational Safety & Risk Sciences (TSRS)

Amgen

Thousand Oaks, California

Job description

Overview

In this role, you drive the development of scalable data infrastructure and analytics for NAMs and translational safety. You collaborate across discovery biology, nonclinical safety, and AI/ML teams to create connected data ecosystems that accelerate decision-making. You design visualizations and pipelines to translate complex data into actionable insights for diverse stakeholders. This position offers impact across Amgen Research with a strong emphasis on translational safety and data-driven science.

Compensation / Benefits
  • Retirement and Savings Plan with company contributions
  • group medical/dental/vision coverage
  • Stock-based long-term incentives
  • Discretionary annual bonus
  • Generous paid time off
  • Flexible work models where possible
Responsibilities
  • Design, develop, and maintain scalable data infrastructure and visualization solutions supporting NAMs initiatives and TSRS workflows
  • Develop and implement databases and registries using Databricks
  • Collaborate with scientific, data engineering, IT, and AI/ML teams to harmonize data structures across nonclinical and clinical safety domains
  • Define metadata standards and ontology mappings for model systems, assays, samples, readouts, validation status, and context of use
  • Support data governance, data quality, and reproducibility across TSRS platforms
  • Conceptualize, design, and build interactive dashboards and visualizations (Spotfire) to enable AI-supported data-driven decision-making
  • Translate complex scientific concepts into clear visualizations and actionable insights for diverse stakeholders
  • Develop pipelines and workflows to integrate NAMs data with enterprise datasets (clinical data) via AI/ML
  • Apply AI/ML approaches to support translational safety analyses, predictive modeling, and NAMs applications
Key requirements
  • PhD, MD, PharmD, or relevant Master's with 3+ years or Bachelor's with 5+ years in Scientific/Data Science
  • Experience building data infrastructure and analytics in Databricks
  • Relational databases, data engineering workflows, and cloud-based analytics
  • Strong Spotfire dashboard development and data visualization
  • Experience integrating data across platforms (Benchling, SharePoint, Databricks, Spotfire, LIMS/ELN)
  • Understanding of NAMs, in vitro models, translational platforms, toxicology, translational safety
  • Strong communication and cross-disciplinary collaboration skills
  • Ability to manage multiple priorities in a fast-paced scientific environment
  • collaboration
  • communication
  • cross-functional partnership
  • Databricks
  • Spotfire
  • SharePoint

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