Overview In this role you will lead early-stage drug product development across complex biologics, including ADCs and oligonucleotides, to deliver stable, manufacturable products for clinical development. You will collaborate across functions to integrate formulation, analytical, and process data, and influence development strategies. You will apply new technologies, including AI/ML, to accelerate workflows and improve decision-making, all while mentoring junior scientists. This role offers a meaningful opportunity to shape patient-focused therapies in a fast-paced, matrixed environment.
Compensation / Benefits- Retirement and Savings Plan
- group medical, dental and vision coverage
- life and disability insurance
- discretionary annual bonus
- stock-based long-term incentives
- flexible work models
Responsibilities- Lead planning, design, execution, and documentation of lab studies in drug product design and process development
- Collaborate across process development, R&D, analytics, regulatory, quality, manufacturing, and external partners to advance programs
- Develop and characterize liquid and lyophilized formulations for complex biologics (ADCs, mAbs, multispecifics)
- Build cross-functional understanding of unit operations to enable scalable drug product development
- Evaluate stability and compatibility under clinically relevant conditions
- Investigate CQAs and modality-specific attributes (e.g., ADC, oligonucleotide)
- Leverage high-throughput and data-driven tools for screening, stability, developability, and processability
- Apply AI/ML, automation, and data science to predictive modeling and decision-making
- Drive continuous improvement and adopt new technologies and standardized methods
- Ensure development approaches are phase-appropriate from discovery to clinical manufacturing
- Provide scientific leadership and mentorship in formulation, stability, and process development
- Author/regulatory support documents, including INDs/CTAs and technology transfer packages
- Support technology transfer with CMOs/CDMOs and manufacturing campaigns
Key requirements- PhD in a relevant field or Master's with 2+ years of science experience or Bachelor's with 4+ years of science experience
- Experience in biologics drug product formulation development, stability assessment, and process development; direct ADC or oligonucleotide experience preferred
- Strong understanding of formulation stability, degradation pathways, and phase-appropriate control strategies
- Experience with analytical/biophysical techniques (UPLC/HPLC, SEC, IEX, LC-MS, etc.)
- Familiarity with clinical-stage development, technology transfer, and risk-based decision-making
- Experience applying AI/ML, automation, or data science to R&D workflows
- Strong communication skills and ability to author technical/regulatory documents
- Ability to work effectively in a fast-paced, matrixed environment
- Mentorship and cross-functional leadership capabilities
- cross-functional collaboration
- clear communication
- mentorship
- biologics drug product formulation
- ADC drug product development
- oligonucleotide formulation and stability (e.g., siRNA)
