S
Not Specified Permanent

Boston, Massachusetts · USA job

Principal Scientist, Machine Learning

Seres Therapeutics

Boston, Massachusetts

Job description

Overview

As Principal Scientist, lead AI/ML and computational initiatives accelerating pharmaceutical R&D from preclinical to clinical stages. You will shape pragmatic AI strategies, develop and benchmark end-to-end, agent-enabled pipelines, and collaborate with PMs and platform ventures. Your work spans omics, biomolecule design, literature mining, and systems biology, tying methods to action through agent-based workflows. You'll mentor teams, influence strategy, and advance cross-portfolio impact in a fast-paced, entrepreneurial setting.

Compensation / Benefits
  • healthcare coverage
  • annual incentive program
  • retirement benefits
  • broad range of other benefits
Responsibilities
  • Lead development, implementation, and reporting of AI/ML and computational projects across preclinical to clinical programs
  • Own build, scaling, benchmarking, and maintenance of agentic systems for end-to-end R&D acceleration
  • Promote AI project best practices and educate cross-functional collaborators
  • Manage and coordinate internal/external scientists and engineers; mentor hires and support recruiting
  • Contribute to project planning, budgets, resources, timelines; surface risks and options early
  • Scout emerging AI/ML literature and landscape; propose new development strategies for PI, PM, and venture portfolios
  • Communicate complex findings to diverse audiences to enable informed decisions
Key requirements
  • Master's or PhD in a relevant field with 5+ years in academic, pharmaceutical, or biotech settings; industry AI/ML experience preferred
  • Proven track record of leadership and decision-making in AI/ML projects
  • Strong technical foundation across Python, modern ML frameworks (PyTorch/JAX/TensorFlow), version control, databases, deep learning architectures
  • Publications, patents, or impactful internal reports demonstrating sustained high performance
  • cross-functional collaboration
  • leadership and mentorship
  • clear communication of complex results
  • Python
  • PyTorch
  • JAX

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