Overview In this Scientist role, you genotypically characterize complex genetically modified models using cutting-edge platforms to support R&D and technology development for drug discovery. You work within a fast-growing science-driven environment and collaborate across teams to advance genotyping workflows and data quality. You will optimize automation to increase throughput and reliability, contributing to meaningful patient outcomes. This position offers hands-on experience with state-of-the-art systems and data analysis in a supportive, on-site setting.
Compensation / Benefits- salary range provided
- annual bonuses or incentive plans
- equity awards
- 401(k) company match
- health and wellness programs
- paid time off
Responsibilities- Process biopsy samples for downstream extraction and genotyping analysis
- Perform high-throughput DNA isolation from embryonic stem cells and rodent biopsies using automation
- Select and implement genotyping methodologies and establish workflow priorities
- Operate Hamilton Liquid Handler applications for qPCR assay retrieval and bulk master mix preparation
- Coordinate aliquoting of qPCR master mixes across processes
- Set up complex qPCR reactions on Beckman i7 Liquid Handlers
- Initiate qPCR using a customized cycling platform
- Collect, organize, and analyze raw data with custom data analysis tools
- Report genotyping results through LIMS and discuss with collaborators as needed
- Perform conventional PCR or Southern Blotting as alternatives to qPCR
- Maintain comprehensive sample management systems and assay inventory
Key requirements- Bachelor's or Master's degree in biology, molecular biology, or related biological sciences with a minimum of 3 years of experience
- Strong motivation and genuine curiosity for rodent genetics
- Maintain scientific rigor and familiarity with best practices
- Leverage automation to drive scientific advancement
- Drive innovation by developing novel approaches and optimizing existing platforms for efficiency and data quality
- multi-tasking in ambiguous environments
- high motivation and curiosity
- scientific rigor
- genotyping methods
- qPCR
- conventional PCR
