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Boston, Massachusetts · USA job

Head of Agentic Biology

Sanofi

Boston, Massachusetts

Job description

Overview

As Head of Agentic Biology within CompAI, you lead the design and deployment of AI-first, end-to-end discovery workflows that accelerate therapeutic programs. You will shape an enterprise-scale computational ecosystem, linking wet-lab data capture with advanced modeling and agentic AI to inform go/no-go decisions. You collaborate across immunology, oncology, neuroscience, and other domains to advance target discovery and validation. This role combines leadership, deep computation expertise, and hands-on delivery to push the frontier of AI-enabled drug discovery. You will influence strategy, build cross-functional teams, and drive measurable impact in early discovery.

Compensation / Benefits
  • health and wellbeing benefits
  • at least 14 weeks' gender-neutral parental leave
  • career growth and opportunities for international moves
  • competitive rewards package
  • work with cutting-edge AI and data platforms
Responsibilities
  • Lead design and deployment of initial agentic bioinformatics workflows automating data capture, analysis, and insight generation across programs
  • Shift from reactive analysis to proactive, predictive, autonomous reasoning in biology
  • Advance target discovery using multi-modal disease data (genetics, genomics, single-cell, proteomics, imaging, clinical)
  • Provide strategic direction for bioinformatics across therapeutic areas and inform go/no-go decisions
  • Translate computational findings into experimental validation strategies
  • Present data-driven recommendations to senior leadership with scientific rigor
  • Design and scale bioinformatics infrastructure using cloud-native architectures and agentic tooling
  • Oversee data modeling, integration, pipelines, AI/ML, DataOps, ModelOps, and cloud platforms
  • Lead big data lake initiatives for Genetic, Transcriptomic, and Proteomic data
Key requirements
  • PhD in a STEM field (AI/ML, Immunology, Biomedical Engineering, Computational Biology, Bioinformatics, etc.)
  • 5+ years of AI/ML experience; biotech/pharma or academia exposure preferred
  • Familiarity with agentic AI frameworks and autonomous workflow orchestration
  • Hands-on experience with AI for Science tools and platforms in biology
  • Knowledge of foundational models in biology and multi-omics data integration
  • Proven leadership of matrix and international teams in biopharma or research
  • Deep expertise in disease/target biology across Sanofi's key areas
  • Experience presenting complex science to senior leadership and at conferences
  • collaborative
  • cross-functional communication
  • consultancy mindset
  • agentic AI frameworks
  • multi-omics data integration
  • AI/ML architectures and evaluation

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