Overview In this LC-MS Bioanalytical Scientist role, you design, validate, and implement quantitative LC-MS/MS methods across small molecules, oligonucleotides, proteins, and complex entities to support discovery and regulated activities. You'll modernize automation and instrumentation, collaborate with cross-functional teams, and deliver data-driven insights. This position provides a pathway to impact GLP preclinical and clinical work while advancing bioanalytical capabilities. You join a collaborative, science-driven culture focused on patient outcomes.
Compensation / Benefits- Retirement and Savings Plan
- health/dental/vision coverage
- life and disability insurance
- flexible spending accounts
- discretionary annual bonus
- stock-based long-term incentives
Responsibilities- Plan, execute, and document quantitative LC-MS/MS bioanalytical experiments
- Develop and implement fit-for-purpose bioanalytical methods with rapid turnaround
- Perform small- and large-molecule bioanalysis in matrices (plasma, urine, CSF, tissues)
- Prepare biological samples via protein precipitation, SPE, LLE, affinity capture, and related techniques
- Organize, analyze, interpret, and present bioanalytical data with data integrity
- Maintain complete, accurate documentation in ELN and lab systems
- Ensure data/records meet regulatory expectations for global submissions
- Author/review study reports, methods, SOPs, memos, regulatory documents
- Communicate results to discovery/development teams; contribute to publications
- Support report quality control, time management, and cross-functional communication
- Follow safety, training, and site procedures; perform housekeeping and operational support
Key requirements- Doctorate degree
- Bachelor's degree with 4 years of relevant industrial/technical experience or Master's with 2 years or Doctorate
- Preferred: CRO/pharma/biotech experience
- Strong expertise in quantitative mass spectrometry on triple quadrupole (QQQ) and HRMS
- Experience with analytical technologies enabling bioanalysis, automation, and micro-sampling
- GLP and GCP experience
- Experience with diverse sample types (blood, plasma, serum, tissues, CSF)
- Hands-on automated sample preparation for LC-MS bioanalysis (protein precipitation, SPE, affinity capture) and high-throughput workflows (KingFisher APEX/FLEX, automated SPE, robotic liquid handlers)
- Experience in regulated bioanalytical assay execution and transfer to CROs
- Ability to work in a fast-paced, multi-project environment with high workload
- Strong problem-solving, project/time management, and collaboration skills
- Supervisory/mentoring experience in a lab setting
- collaboration
- problem-solving
- time management
- quantitative mass spectrometry (QQQ, HRMS)
- bioanalytical method development
- automation and micro-sampling
