Overview As Principal Scientist in Ophthalmology Research, you will lead hands-on in vivo programs from discovery to candidate nomination and early development. You'll generate high-quality data and guide cross-functional teams to inform strategic decisions. The role blends bench leadership with mentoring a small team to foster a collaborative, inclusive culture. You will stay at the forefront of ophthalmology science to shape translational strategies and potential therapies. This position offers the opportunity to impact patient outcomes through cutting-edge research in a global company.
Compensation / Benefits- Medical, Dental and Vision Insurance
- Generous Paid Time Off (vacation, sick leave, holidays, year-end shut down)
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive (eligible positions)
- Long Term Incentive Plan (eligible positions)
Responsibilities- Design, execute, troubleshoot, and interpret in vivo pharmacology studies in ophthalmology to evaluate therapeutic candidates
- Contribute hands-on execution while providing scientific leadership to project teams
- Integrate in vitro and in vivo data to generate insights for program strategy and go/no-go decisions
- Lead interdisciplinary efforts with internal and external partners to ensure timely study execution
- Develop translational research strategies to advance disease biology understanding, pharmacology, and efficacy
- Contribute to preclinical data packages supporting milestones and regulatory submissions
- Foster an inclusive, collaborative environment and maintain robust cross-functional relationships
- Maintain accurate records and communicate findings through presentations and reports
- Stay current with literature and advances to identify new opportunities
Key requirements- PhD with 8+ years of postdoctoral/industry experience in ophthalmology, neuroscience, biology, pharmacology, or related field
- Deep ophthalmic research expertise and track record advancing programs
- Hands-on experience designing and interpreting in vivo ophthalmology studies for drug discovery or development
- Experience evaluating modalities including small molecules, biologics, gene/cell/RNA therapies
- Technical expertise in ocular imaging, visual function testing, and histology/histopathology
- Ability to independently develop study strategies and translate data into program decisions
- Experience leading programs in a matrixed environment and collaboration across functions
- Publications, patents, or contributions to successful drug discovery/development
- Strong communication and interpersonal skills
- collaborative and interpersonal
- mentoring and team-building
- strong written and verbal communication
- ocular imaging (OCT, fundus imaging)
- ERG and vision-dependent behavior assays
- retinal histology/histopathology
